Taimour Langaee Selected Research

Investigational Drugs

1/2020	Pharmacokinetic and Biochemical Profiling of Sodium Dichloroacetate in Pregnant Ewes and Fetuses.
1/2018	Age-Related Changes in Expression and Activity of Human Hepatic Mitochondrial Glutathione Transferase Zeta1.
2/2012	Prenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetate.
10/2008	Role of dichloroacetate in the treatment of genetic mitochondrial diseases.

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Taimour Langaee Research Topics

Disease

8	Neoplasms (Cancer) 12/2021 - 02/2012
4	Coinfection 01/2021 - 01/2019
4	Tuberculosis (Tuberculoses) 01/2021 - 01/2018
3	Hypertension (High Blood Pressure) 01/2022 - 01/2012
3	Osteonecrosis (Kienbock's Disease) 12/2021 - 01/2019
3	HIV Infections (HIV Infection) 01/2021 - 01/2019
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 10/2008
3	Lactic Acidosis 01/2020 - 02/2012
2	Osteoporosis 12/2021 - 01/2019
2	Cardiotoxicity 01/2021 - 01/2018
2	Heart Failure 01/2021 - 01/2020
2	Pain (Aches) 01/2019 - 01/2018
2	Chronic Pain 01/2019 - 02/2012
1	Body Weight (Weight, Body) 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Hemorrhage 01/2022
1	Inflammation (Inflammations) 01/2022
1	Multiple Myeloma 01/2021
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2020
1	Pyruvate Dehydrogenase Complex Deficiency Disease 04/2018
1	Cancer Pain 01/2018
1	Ischemic Stroke 01/2018
1	Alcoholic Fatty Liver 01/2018
1	Fibrosis (Cirrhosis) 01/2018
1	Neoplasm Metastasis (Metastasis) 01/2018
1	Hematologic Neoplasms (Hematological Malignancy) 01/2018
1	Acute Coronary Syndrome 01/2018
1	Non-alcoholic Fatty Liver Disease 01/2018
1	Liver Neoplasms (Liver Cancer) 06/2016
1	Hepatocellular Carcinoma (Hepatoma) 06/2016
1	Essential Hypertension 03/2016
1	Infections 01/2015

Drug/Important Bio-Agent (IBA)

5	Pharmaceutical PreparationsIBA 01/2022 - 01/2018
4	Investigational DrugsIBA 01/2020 - 10/2008
4	Glutathione Transferase (Glutathione S-Transferase)IBA 04/2018 - 02/2012
3	Diphosphonates (Bisphosphonates)IBA 12/2021 - 01/2019
2	omega-Chloroacetophenone (Mace)IBA 01/2022 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2020
2	MicroRNAs (MicroRNA)IBA 01/2022 - 03/2016
2	Clopidogrel (Plavix)FDA Link 01/2022 - 01/2018
2	Nevirapine (Viramune)FDA Link 01/2021 - 10/2019
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2020 - 06/2013
2	Dichloroacetic AcidIBA 01/2020 - 02/2012
2	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2019 - 01/2018
2	Opioid Analgesics (Opioids)IBA 01/2019 - 01/2018
1	Metformin (Glucophage)FDA LinkGeneric 01/2022
1	TabletsIBA 01/2022
1	Letrozole (Femara)FDA LinkGeneric 01/2022
1	Saline SolutionIBA 01/2022
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2022
1	Cytochrome P-450 CYP2C19IBA 01/2022
1	Metoprolol (Toprol-XL)FDA LinkGeneric 01/2022
1	Minocycline (Cyclops)FDA LinkGeneric 01/2022
1	NucleosidesIBA 01/2021
1	Pyruvic Acid (Pyruvate)IBA 01/2021
1	Lamivudine (Epivir)FDA Link 01/2021
1	abacavir (Ziagen)FDA Link 01/2021
1	Proteasome InhibitorsIBA 01/2021
1	Sirtuin 1IBA 01/2021
1	lactate dehydrogenase 1 (LDH1)IBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	Zidovudine (Retrovir)FDA LinkGeneric 01/2021
1	Reverse Transcriptase InhibitorsIBA 01/2021
1	carfilzomibIBA 01/2021
1	Mineralocorticoid Receptor AntagonistsIBA 01/2020
1	Spironolactone (Aldactone)FDA LinkGeneric 01/2020
1	Tenofovir (Viread)FDA Link 12/2019
1	Cytochrome P-450 CYP2B6 (CYP2B6)IBA 10/2019
1	efavirenz (Sustiva)FDA Link 01/2019
1	Tramadol (K315)FDA LinkGeneric 01/2019
1	Codeine (Codeine Phosphate)FDA LinkGeneric 01/2019
1	Genetic Markers (Genetic Marker)IBA 01/2019
1	nasIBA 01/2018
1	thiopurine methyltransferase (thiopurine S-methyltransferase)IBA 01/2018
1	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 01/2018
1	2-mercaptopurineIBA 01/2018
1	Pioglitazone (Actos)FDA Link 01/2018
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2018
1	Glutathione (Reduced Glutathione)IBA 01/2018
1	Isoniazid (Ftivazide)FDA LinkGeneric 01/2018
1	Rifampin (Rifampicin)FDA LinkGeneric 01/2018
1	glyoxylic acid (glyoxylate)IBA 06/2016
1	ChloridesIBA 06/2016
1	Proteins (Proteins, Gene)FDA Link 06/2016
1	EnzymesIBA 06/2016
1	beta-Lactamases (beta-Lactamase)IBA 01/2015
1	beta Lactam AntibioticsIBA 01/2015
1	Biomarkers (Surrogate Marker)IBA 02/2012
1	maleylacetoacetate isomeraseIBA 02/2012
1	AcidsIBA 02/2012
1	Tyrosine (L-Tyrosine)FDA Link 02/2012
1	HDL CholesterolIBA 01/2012

Therapy/Procedure

12	Therapeutics 01/2021 - 06/2016
2	Stents 01/2022 - 01/2018
1	Percutaneous Coronary Intervention 01/2022
1	Art Therapy 10/2019
1	Drug Therapy (Chemotherapy) 01/2018
1	Precision Medicine 01/2018
1	Pain Management 01/2018
1	Ketogenic Diet 06/2013